Master Alliance Provisions Guide (MAPGuide)

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Agreement title
Effective date
Partner type
Technology
Development stage
UK Secretary of State - Roche, REGN-COV2 Supply Agreement
2021
Government
Industry
Drug
Late clinical (Phase 3)
Commercialization
European Commission - AstraZeneca, COVID-19 Vaccine Advance Purchase Agreement
2020
Government
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
Alnylam Pharmaceuticals - University of British Columbia- AlCana Technology, Sponsored Research Agreement
2009
Academic institution
Industry
Drug
Vaccine
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
PATH - Aridis, Rotavirus Vaccine Development Agreement
2007
Industry
Product development partnership
Vaccine
Early clinical (through Phase 2)
AXA Prime Impact Master Fund - Revelation Biosciences, Diagnostics & Therapeutics for Viral Infections, Global Health Agreement
2020
Funder
Industry
Diagnostic
Drug
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Yale University - BIND Biosciences, Cancer Therapeutic, Exclusive License Agreement
2013
Academic institution
Industry
Drug
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Biological E - Dynavax Technologies, COVID-19 Vaccine Adjuvant Supply Agreement
2021
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
Boston University Startup Exclusive License Template
2012
Academic institution
Industry
Non-profit research organization
Product development partnership
Device
Diagnostic
Drug
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Field Testing
CARB-X Portfolio Company Agreement Template
2019
Academic institution
Funder
Industry
Non-profit research organization
Product development partnership
Diagnostic
Drug
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Cellscript - BioNTech mRNA Technology Patent Sublicense
2016
Industry
Vaccine
Preclinical
CEPI - Dynavax, COVID-19 Material Reservation Agreement
2021
Funder
Industry
Vaccine
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
CEPI - Valneva, Chikungunya Vaccine Funding Agreement
2019
Funder
Industry
Vaccine
Preclinical
Early clinical (through Phase 2)
Sanofi - Translate Bio, Influenza and COVID-19 Vaccine Collaboration & License Agreement
2020
Industry
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
CSIC - MPP (C-TAP), COVID-19 Vaccine, Patent and Material License Agreement
2023
Government
Multilateral organization
Vaccine
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
CSIC - MPP (C-TAP), COVID-19 Diagnostic, Patent & Material License Agreement
2021
Government
Multilateral organization
Diagnostic
Commercialization
DNDi - BioDelivery Sciences International, Visceral Leishmaniasis Research Collaboration Agreement
2009
Industry
Product development partnership
Drug
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Elkurt - Ocean Biomedical, Malaria Vaccine, Exclusive License Agreement
2021
Industry
Vaccine
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
DNDi/GARDP - Entasis, Gonorrhoea Medication, Collaboration Agreement
2017
Industry
Product development partnership
Drug
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Fiocruz - AstraZeneca, COVID-19 Technological Order Agreement
2021
Government
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
Fiocruz - AstraZeneca, COVID-19 Vaccine Technology Transfer Agreement
2021
Government
Industry
Vaccine
Commercialization
Gilead, HIV Therapeutic (Lenacapavir) Template License Agreement
2024
Industry
Drug
Late clinical (Phase 3)
Commercialization
Harvard - Tectonic Therapeutic, License Agreement
2022
Academic institution
Industry
Drug
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
MedinCell - MPP, Malaria Vector Control (mdc-STM/ivermectin formulation) License Agreement
2022
Industry
Multilateral organization
Drug
Late clinical (Phase 3)
Commercialization
Merck - Bioprotection Systems Corp., Ebola Vaccine License & Collaboration Agreement
2014
Industry
Vaccine
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Moderna – Lonza, COVID-19 mRNA Vaccine & Therapies, Manufacturing & Process Development Agreement
2020
Industry
Drug
Vaccine
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Medigen - MPP (C-TAP), COVID-19 Vaccine, Patent and Know How License Agreement
2023
Industry
Multilateral organization
Vaccine
Commercialization
PHS - Biosyn, HIV Prophylactic Exclusive License Agreement
2003
Government
Industry
Device
Drug
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
NIH - GeoVax, Non-Exclusive Patent and Biological Materials License Agreement
2020
Government
Industry
Vaccine
Preclinical
Commercialization
NIH - UniQure, AAV5 Gene Therapies Exclusive and Non-Exclusive License Agreement
2011
Government
Industry
Drug
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
US Department of Defense - Novavax, COVID-19 Vaccine Development Agreement
2020
Government
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
Ocugen-BBIL, COVID-19 Vaccine (Covaxin), Co-development, Supply & Commercialization Agreement
2021
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
PHS - Aridis, Rotavirus Vaccine Exclusive and Non-Exclusive License Agreement
2005
Government
Industry
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
PHS (NIH/CDC/FDA), Model Exclusive Patent License Agreement
2015
Academic institution
Government
Industry
Multilateral organization
Product development partnership
Device
Diagnostic
Drug
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
PHS (NIH/CDC/FDA), Model Non-Exclusive Patent License Agreement
2015
Academic institution
Government
Industry
Multilateral organization
Product development partnership
Device
Diagnostic
Drug
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Population Council - TherapeuticsMD, Nestorone Contraceptive Ring, License Agreement
2018
Industry
Non-profit research organization
Device
Commercialization
Field Testing
Academic Institution - Company, Research Collaboration Agreement
2016
Academic institution
Industry
Vaccine
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Field Testing
Shionogi - GARDP, Cefiderocol License Agreement
2022
Industry
Product development partnership
Drug
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
Spinal Muscular Atrophy Foundation - PTC Therapeutics, Spinal Muscular Atrophy Therapeutics Sponsored Research Agreement
2006
Industry
Non-profit research organization
Drug
Discovery/Concept
Preclinical
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization
UK Medical Research Council - Indevus Pharmaceuticals, Antiviral Microbicide, Collaborative Research and Licensing Agreement
2005
Government
Industry
Drug
Late clinical (Phase 3)
University of Washington - MPP, Long-acting Injectable HIV Treatment License Agreement
2021
Academic institution
Multilateral organization
Drug
Preclinical
Valneva - Serum Institute of India, Chikungunya Vaccine License Agreement
2024
Industry
Vaccine
Late clinical (Phase 3)
Commercialization
Visterra - Serum Institute of India, Dengue Fever Therapeutic, License and Collaboration Agreement
2015
Industry
Drug
Early clinical (through Phase 2)
Late clinical (Phase 3)
Commercialization

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 	What is the process for managing liability claims?
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 	What is the required timeline for sharing information?
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 	Do the parties have the right to verify the information reported?

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 	What is the scope of the licensed intellectual property?
 	What is the territory of the license?
 	Is the license exclusive or non-exclusive?
 	Are there any restrictions on the use of the licensed intellectual property?
 	Are there any specific obligations to exploit the licensed intellectual property?
 	Can the licensee grant sublicenses to third parties?
 	Will products manufactured under license be marketed as branded or generic? (i.e. will they bear the licensor’s trademarks/trade dress)

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What are the mechanisms to limit exposure to additional payments or expenses?
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                    [count] => 13
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What are the acceptable publication channels?
Is compliance with a specific open access policy required?
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                    [description] => 
                    [parent] => 53
                    [count] => 41
                    [filter] => raw
                    [parent_name] => Business model
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                    [name] => Regulatory strategy
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                    [description] => 
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                    [filter] => raw
                    [parent_name] => Business model
                    [parent_slug] => business-model
                )

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                    [name] => Representations & warranties
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                    [description] => Should the parties make any warranties, and if so, what is the scope?
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                    [count] => 98
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                    [parent_name] => Liability
                    [parent_slug] => liability
                )

            [86] => WP_Term Object
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                    [name] => Technology transfer
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                    [description] => What is included in the technology and/or materials to be transferred?
What are the responsibilities of each party to in relation to the transfer of materials and/or technology?
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                    [parent_name] => Protecting & sharing information
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 	What is the term of the agreement? Is it tied to the timeline of the project or license grants?

Termination

 	Under what circumstances may a party terminate or withdraw from the agreement?

Effects of Termination

 	What are the effects of termination or withdrawal by a party?

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                    [parent_name] => 
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                )

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                    [description] => 
                    [parent] => 52
                    [count] => 98
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                    [taxonomy] => issue
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                    [name] => Territory access commitments
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                    [description] => 
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 	Should the developer be required to commit a proportion of the product manufactured to a certain country or purchasing organization?
 	Should the developer be required to identify a third party that could fulfill supply requirements for the access territories in the event that the developer does not?
 	Should the agreement include any anti-diversion provisions?

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                    [count] => 63
                    [filter] => raw
                    [parent_name] => Equitable access
                    [parent_slug] => access-to-medicines
                )

        )

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                    [description] => 
 	How should equitable or global access be defined?
 	Should the developer be required to comply with an equitable access policy?
 	Should the developer be required to establish an access plan?

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                    [filter] => raw
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                    [description] => 
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                    [filter] => raw
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                )

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                    [taxonomy] => issue
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                    [parent_name] => 
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                )

            [clinical-trial-conduct] => WP_Term Object
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                    [name] => Clinical trial conduct
                    [slug] => clinical-trial-conduct
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                    [term_taxonomy_id] => 371
                    [taxonomy] => issue
                    [description] => 
                    [parent] => 53
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                    [filter] => raw
                    [parent_name] => Business model
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                )

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                    [name] => Confidentiality
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 	What are the obligations of the parties to protect confidential information?
 	Are there any exceptions to the confidentiality obligations?
 	Are the parties permitted to make public announcements related to the project?
 	Can the parties use each other’s name and logo for general marketing materials?

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                    [count] => 112
                    [filter] => raw
                    [parent_name] => Protecting & sharing information
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            [donation] => WP_Term Object
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                    [name] => Donation
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                    [taxonomy] => issue
                    [description] => 
                    [parent] => 46
                    [count] => 5
                    [filter] => raw
                    [parent_name] => Equitable access
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                    [description] => 
                    [parent] => 52
                    [count] => 96
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            [ensuring-continuity] => WP_Term Object
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                    [name] => Ensuring continuity
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 	Under what circumstances can the continuity rights be exercised? (What are the conditions precedent?)
 	What is an appropriate scope for the continuity rights? What are the rights and obligations of each party?
 	Should related license grants vest upon execution of the agreement, or at a later stage in development?
 	Should there be an escrow requirement?
 	Should there be any restrictions on the developer’s ability to transfer project-related intellectual property to a third party?

                    [parent] => 46
                    [count] => 55
                    [filter] => raw
                    [parent_name] => Equitable access
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            [access-to-medicines] => WP_Term Object
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                )

            [roles-responsibilities] => WP_Term Object
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                    [name] => Governance
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                    [taxonomy] => issue
                    [description] => 
 	Do the parties govern the project through a joint steering committee ("JSC")? If so, what are the parties expressly designated roles and responsibilities with respect to the JSC?
 	Are there other committees, important governance bodies, or designated individual positions? What are the parties' roles and responsibilities with respect to them?
 	Are the parties required to meet in accordance with a defined schedule for decision-making and progress reporting activities?
 	What are the resolution mechanisms for disputes related to the agreement?
 	Are there any requirements for policies or procedures to manage potential conflicts of interest?

                    [parent] => 53
                    [count] => 98
                    [filter] => raw
                    [parent_name] => Business model
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 	What is the process for managing liability claims?
 	Are there government or other types of indemnification schemes?
 	Is there any limitation or monetary cap on each party’s liabilities under the agreement?

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                    [filter] => raw
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            [information-sharing-information-sharing] => WP_Term Object
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                    [description] => 
 	What financial and project progress information must be shared between the parties?
 	What is the required timeline for sharing information?
 	How is the receiving party permitted to use the information received?
 	Do the parties have the right to verify the information reported?

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                    [filter] => raw
                    [parent_name] => Liability
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            [liability] => WP_Term Object
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                    [parent] => 0
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                    [parent_name] => 
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                )

            [license-grants] => WP_Term Object
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                    [description] => 
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 	What is the scope of the licensed intellectual property?
 	What is the territory of the license?
 	Is the license exclusive or non-exclusive?
 	Are there any restrictions on the use of the licensed intellectual property?
 	Are there any specific obligations to exploit the licensed intellectual property?
 	Can the licensee grant sublicenses to third parties?
 	Will products manufactured under license be marketed as branded or generic? (i.e. will they bear the licensor’s trademarks/trade dress)

                    [parent] => 48
                    [count] => 107
                    [filter] => raw
                    [parent_name] => Intellectual property
                    [parent_slug] => ip-ownership
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            [ownership-ip] => WP_Term Object
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                    [name] => Ownership of IP
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                    [description] => 
                    [parent] => 48
                    [count] => 80
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                    [parent_name] => Intellectual property
                    [parent_slug] => ip-ownership
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            [royalties-and-payments] => WP_Term Object
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                    [description] => What is the payment structure under this agreement? 
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            [outbreak-preparedness] => WP_Term Object
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                    [slug] => outbreak-preparedness
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                    [term_taxonomy_id] => 102
                    [taxonomy] => issue
                    [description] => 
                    [parent] => 46
                    [count] => 13
                    [filter] => raw
                    [parent_name] => Equitable access
                    [parent_slug] => access-to-medicines
                )

            [supply-purchase-of-products] => WP_Term Object
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                    [taxonomy] => issue
                    [description] => 
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            [information-sharing] => WP_Term Object
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                    [taxonomy] => issue
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                    [count] => 0
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                    [parent_name] => 
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                )

            [protection-results] => WP_Term Object
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                    [term_id] => 90
                    [name] => Protection of IP
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                    [term_taxonomy_id] => 90
                    [taxonomy] => issue
                    [description] => 
                    [parent] => 48
                    [count] => 82
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                    [parent_name] => Intellectual property
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            [publication-of-results] => WP_Term Object
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                    [taxonomy] => issue
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What is the required timeline for making data available?
What are the acceptable publication channels?
Is compliance with a specific open access policy required?
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                    [count] => 67
                    [filter] => raw
                    [parent_name] => Protecting & sharing information
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            [quality-management] => WP_Term Object
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                    [taxonomy] => issue
                    [description] => 
                    [parent] => 53
                    [count] => 41
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                    [parent_name] => Business model
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            [warranties] => WP_Term Object
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                    [taxonomy] => issue
                    [description] => Should the parties make any warranties, and if so, what is the scope?
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                    [count] => 45
                    [filter] => raw
                    [parent_name] => Protecting & sharing information
                    [parent_slug] => information-sharing
                )

            [term-and-termination] => WP_Term Object
                (
                    [term_id] => 52
                    [name] => Term & termination
                    [slug] => term-and-termination
                    [term_group] => 0
                    [term_taxonomy_id] => 52
                    [taxonomy] => issue
                    [description] => Term

 	What is the term of the agreement? Is it tied to the timeline of the project or license grants?

Termination

 	Under what circumstances may a party terminate or withdraw from the agreement?

Effects of Termination

 	What are the effects of termination or withdrawal by a party?

                    [parent] => 0
                    [count] => 0
                    [filter] => raw
                    [parent_name] => 
                    [parent_slug] => 
                )

            [term-of-agreement] => WP_Term Object
                (
                    [term_id] => 76
                    [name] => Term of agreement
                    [slug] => term-of-agreement
                    [term_group] => 0
                    [term_taxonomy_id] => 76
                    [taxonomy] => issue
                    [description] => 
                    [parent] => 52
                    [count] => 98
                    [filter] => raw
                    [parent_name] => Term & termination
                    [parent_slug] => term-and-termination
                )

            [termination-and-withdrawal] => WP_Term Object
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                    [term_id] => 74
                    [name] => Termination & withdrawal
                    [slug] => termination-and-withdrawal
                    [term_group] => 0
                    [term_taxonomy_id] => 74
                    [taxonomy] => issue
                    [description] => 
                    [parent] => 52
                    [count] => 102
                    [filter] => raw
                    [parent_name] => Term & termination
                    [parent_slug] => term-and-termination
                )

            [territory-access-commitments] => WP_Term Object
                (
                    [term_id] => 282
                    [name] => Territory access commitments
                    [slug] => territory-access-commitments
                    [term_group] => 0
                    [term_taxonomy_id] => 282
                    [taxonomy] => issue
                    [description] => 
 	How should ‘territory’ be defined under the agreement? Should the definition make a distinction between different types of purchaser (e.g. public sector vs. private sector)?
 	Should the developer be required to apply for regulatory approval in priority access markets?
 	Should the developer be required to commit a proportion of the product manufactured to a certain country or purchasing organization?
 	Should the developer be required to identify a third party that could fulfill supply requirements for the access territories in the event that the developer does not?
 	Should the agreement include any anti-diversion provisions?

                    [parent] => 46
                    [count] => 63
                    [filter] => raw
                    [parent_name] => Equitable access
                    [parent_slug] => access-to-medicines
                )

        )

    [filter_issues:GHIAA2019\MapguideSearch:private] => Array
        (
        )

)